Laser precision fabrication offers the ability for the surface and in-volume patterning, at the micro- and the nano- lengthscales, of practically all classes of solid materials, including biomaterials. The inhomogeneous energy absorption along with material resolidification and related self-assembly phenomena, are the key factors towards precise control of the morphological features for various applications, including tailoring of wettability, controlling fluid transport, tuning of adhesion and friction, tailoring optical properties, as well as improving the biocompatibility and bioactivity of tissue scaffolds. Apart from self-assembled, (pseudo)periodic and hierarchical structures formation, laser precision micro/nano fabrication can be employed for direct writing via material ablation, welding and sintering.